Milano is about an 11-year-old boy who doesn't talk, but expresses himself through sign language. He is raised by his father, who himself grew up in an institution and does not really know how to raise a young child. They live on a social housing estate and try to make the best of it. When Milano is home alone, he is able to stay with Renée, a rich woman from the neighboring villa district who seemingly has everything going for her. Then his mother suddenly re-enters their lives, and nothing is the same anymore.